In order to enable the verification and management of relay protection setting more scientific and effective, an on-line verification of relay protection setting considering electric betweenness is presented. Through the node electric betweenness and line node betweenness system integrated risk assessment, and put it as a measure of the level of protection of importance. Then, verify all protection settings based on protection importance from high to low order online. The simulation and analysis of IEEE14-bus system proved the method feasible and correct, which avoids the shortage of traditional setting checking randomly, and is of great significance to improve the security and stability of power system.