As an important component of the distribution network, virtual power plants (VPPs) can help to increase the management and utilization efficiency of new energy sources, and improve the operational safety, stability, and economy. In order to further improve the economic efficiency of the operation of distribution network, this article studies the economic operation problem of multiple VPPs including photovoltaic and wind power systems based on the framework of multiple VPPs operation. The operation problem of multiple VPPs is modeled as a nonlinear mixed integer programming (NMIP) form. The McCormick linearization method is used to transform the original problem into a linear programming formulation that is easy to solve. The effectiveness of the method is verified through simulation experiments, and results show that compared to independent operation, the collaborative operation mode described in the article can reduce the overall operating cost by about 10%, which improves the economic efficiency of distribution network operation.