Line loss management of distribution networks is an important part ofSthe management of the power supply enterprises, because it plays a very important role in improvingSeconomic benefits and promoting energy conservation. Because of the poor interoperability with other systems and easily split workflow in the existing line loss management of distribution network, it is likely to form islands and seriously affects line loss management results. This paper will design a line loss management system based on Service-Oriented Architecture (SOA). This system has the multipoint, characteristics of asynchronous communication, and it can be completely decoupled in space, time as well as control flow, so it is very suitable for line loss management application system where information is exchanged frequently and dynamic is strong .The line loss management system based on SOA has strong commonality, easy maintenance and can achieve interoperability between line loss management system and other systems. SO, it can improve the efficiency and the level of line loss management.