Partial discharge(PD)is the main inducement of insulation deterioration for power transformers, so the location of partial discharge is crucial to the safe operation of power grid. Location of partial discharge should first clarify the orientation of partial discharge. This paper presents a focused beamforming method based on the minimum variance distortion-less response signal (MVDR) to simulate the location of single partial discharge source of transformer, the integration of MVDR orientation estimation and focused beamforming has higher resolution and lower side-lobe level than the conventional focusing beam forming (CBF) in locating and the aliasing effect can be reduced. The present method also has strong ability of EMC (Electro Magnetic Compatibility), good system stability and it can carry out real-time monitoring. In the end of this paper, the correctness and validity of the present method has been proved by spatial spectrum simulation.