Power grid boost transformation is an important technical renovation measure of power grid enterprises to improve the grid transmission capacity and standardization of voltage grade. According to the basic principles of energy savings calculation from national standard "GB / T 28750-2012 General technical rules for measurement and verification of energy savings ", combined with the actual situation of the construction and operation of power grid, this paper presents a calculation model and method of energy savings measurement and verification for power grid boost transformation that can accurately reflect the energy-saving and environmental benefits of the power grid boost transformation.