For research and use of radioactive material in an urban environment, appeared in the process of radioactive material in the storage of the accidents such as illegal movement, theft and leak can't make the right response in time, and the regulation technology can't achieve real-time dynamic monitoring of radioactive materials, this paper proposes a wireless intelligent remote security system based on ZigBee technology design, with different peripheral sensors to complete intelligent monitoring of it, uses the signal strength indicator value to complete to determine the storage safety of radioactive substances.The experimental results show that the system has stable performance, high sensitivity, has broad application prospects.