The high precision and wide output DC power is used for aircraft measurement and control system, in this paper applying single-chip computer(C8051F005 MCU) as the core, and high speed and high precision components(OPA551PA, AD780), optimized the structure of circuit, a high precision DC monitoring power system was built with multi-output . The design DC monitoring power through rigorous testing demonstrated with well stable and high precision output (up to ±0.05V) performances, satisfies the requirement of measuring and control power supply system.