The increase of UHV DC/AC and renewable energy power generation makes the power system more complex. Especially, the capacity of UHVDC transmission is huge. Once the DC lockout accident happens, the power of the receiving end will be seriously deficient, which will bring great impact on the safe and stable operation of the power grid. Conventional treatment will remove a lot of load. Proper preventive control measures can increase the stability margin of power grid and reduce the pressure of power grid when faults occur. Based on the definition of active response load classification, a voltage responsive load ZIP model is established. By means of OLTC voltage regulation and combining with the characteristics of load active response, the preventive control strategy based on active response load voltage regulation is proposed, which can effectively improve the static voltage value that can reduce the probability of accident and improve the transient voltage margin after accidents that can reduce the proportion of load to be removed after the accident. The simulation results in a Henan example show the effectiveness of the strategy.