With the rapid development of the power grid, the types and quantity of new equipment put into operation are increasing year by year. The existing methods of manual preparation of start-up scheme have problems such as low level of intelligence and poor reliability, which can not meet the development needs of the large power grid and safe and stable operation objectives. Therefore, this paper studied the intelligent programming system of the startup scheme of new power grid equipment. Firstly, the operation type of new equipment put into operation and the characteristics of start-up scheme are analyzed. Then, based on the D5000 intelligent dispatching platform, the required data was obtained, and the B/S architecture system was used to build an intelligent compilation system for the startup scheme of new power grid equipment. The compilation, review process, operation and verification functions of new equipment were designed. Finally, the system function test results show that the intelligent preparation system can effectively reduce the workload of operators, improve the risk management and control of new equipment put into operation, and play an important role in ensuring the safe and stable operation of the power system.