To improve the efficiency of eliminate faults for smart grid, a dispatching scheme of faults based on measurement big data of smart meters is proposed. First, through distribution network state estimation method, in which devices with fault are viewed as temporary loads, and error detection is expanded to non-intrusive fault detection, faults can be located remotely with variable weight matrix based on measurement big data. Towards the issue of repairmen dispatching considering the emergency degree of orders, an iterated local search (ILS) based method is exploited. Experimental results show the practicability of the proposed approach.