In view of the poor ability to resist disturbance and dynamic response lag of Buck converter, the DMC-PID algorithm which is based on output voltage differential coefficient and one cycle control (OVDC-OCC) method for DC/DC converter is brought forward. It combines DMC algorithm with PID control to takes advantage of PID’s anti-interference ability and DMC’s adaptability to inertia and delay. In order to improve the control effect of the system which combines DMC algorithm with PID control in the series and parallel way, according to different working condition on the system are simulated. The results are presented, which show the effectiveness of the control strategy, with better robustness and anti-disturbance performance, for it improves the dynamic and static system performance .The DMC-PID parallel control system is superior to DMC-PID cascade control system.