A new de-noising method integrated with variational mode decomposition (VMD) and wavelet adaptive threshold algorithm is presented in this paper. The method of the de-noising process is as follows: firstly, the noise signal is decomposed by VMD, and then the noises contained in the high frequency modal components in the VMD decomposition components are reduced with the wavelet adaptive threshold filtering. The components of de-noising are reconstructed with other modal components. Three examples show that the proposed method can effectively reduce the signal noise and has wide adaptability.